HSP70 1A 抗体 (AA 300-641)
Quick Overview for HSP70 1A 抗体 (AA 300-641) (ABIN7114900)
抗原
See all HSP70 1A (HSPA1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 300-641
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原理
- HSPA1A antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 300-641aa
Immunogen: heat shock 70kDa protein 1A
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亚型
- IgG1
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应用备注
- WB: 1:2000-1:40000 IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))
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别名
- HSPA1A
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背景
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Synonyms: Heat shock 70 kDa protein 1A|Heat shock 70 kDa protein 1 (HSP70-1, HSP70.1)|HSPA1A|HSP72|HSPA1|HSX70
Background: HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines.(21373891)
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分子量
- 66-70 kDa
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基因ID
- 3303
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UniProt
- P0DMV8
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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